It can, with a little work. The entire system is based around rolling 1 20-sided dice, with the number required to roll being higher or lower depending on difficulty and skills or powers effectively adding to the number the dice yield. For example, a DC (difficulty check, the number required on the roll) of 10 would represent something that someone would be able to accomplish, say, half the time, even if they have no training or experience in the area. A DC of 35 would be something impossible for someone without a ton of experience, and even then would be extremely difficult and possible only under the best of scenarios. It's a pretty simple system, and relatively easy to customize. In Mechamorphosis, I think they scale things (in terms of humans or smaller transformers) such that at each size scale you use the same system, but in a situation where two different size scales are relevant, a scaling factor is applied to the DCs and end results. So, for example, an attack that would do 4 damage to another Transformer would do 4 x 10 (scaling factor) = 40 damage to a mere human, more than enough to kill most fleshling targets. As I said earlier in the thread, it can get complicated. Still, I think its important to remember that a good game is more dependent on story and player interaction and thought than on numerics, so developing a system that accounts for every conceivable option isn't at all necessary.