I certainly wasn’t seeking out a relatable episode to current times while I was scrolling through G1 episodes on Tubi, but for some reason I clicked on Cosmic Rust to watch as I had my morning coffee just now. Considering this was written 35 years ago, it hits bizzarly on the nose right now. Not to get too political, but even Megatron was smart enough to rely on Perceptor, you know....a scientist, to cure him. Also, Optimus does not practice social distancing! Transformers: Generation 1 S02:E44 - Cosmic Rust
I watched it recently and it's still one of my favourite G1 episodes. Even when the real life crisis started, I could almost hear Bumblebee's line, "Somebody's gotta do something, Prime. I never thought the end would come like this." Hopefully, our real life crisis will end soon.
Optimus was at least wearing a mask. Plus, he's (supposed to be) a doctor and a scientist, so there's that. EDIT: I didn't realize that this was an old thread, my bad.