Discussion in 'General Discussion' started by DecepticonSpike, Sep 24, 2009.
A world first: Vaccine helps prevent HIV infection - Yahoo! News
Well, were getting closer.
Now all we need is a vaccine for herpes and genital warts and we can run fearless, headstrong into the wind.
And more importantly, into Bangkok.
Getting closer to put an end to HIV/AIDS.
excellent ill be glad to see AIDS wiped out
At the moment, one is forced to settle for the finer things in life: purity, and love, and innocence. But come the day of these vaccines, it's down with the trousers, out with the old chap, and "Come on ladies, come on gentlemen, come on you trannies, fruits of the forest, satyrs - come slide down the greasy pole of my depravity! Now bring the chickens!"
Oh god, that last part might get some of our resident furries over-excited.
In other words, "stick it in her pooper"?
*slowly backs away from sledge*
That's GREAT!! Now how the hell are we going to test it?
I believe you would have to have subjects who already have the virus who are willing to test it. It pretty much goes against ethics to test it on humans, but I think it has to be done. Although it was probably first tested on primates, I think they have the same HIV as we do. The same with any vaccine, there are the people out there who feel well they have something to gain by this and nothing to lose.
they already tested it in Indonesia where AIDS is rampant and it was effective 35% of the time which is the best result so far and those participated in the study get free medical treatment of they got AIDS
Death row prisoners?
Maybe for a reduced sentence.
...its about f***ing time.
this will benefit millions. but i hope some idiots dont see this as sigb to have sex like crazy... sigh, it probably will.
Woohoo! Let the free love resume! The 60's/70's FTW!
Eh, I just can't get too excited about this right now. Maybe it's because I'm in the field and have seen a fair number of people present the "next big vaccine" against HIV that turns out to protect only a minority of test subjects and induces unconvincing immune responses. Hell, the Merck vaccine had a lot of potential too, and that crashed and burned. I'd need to see some more information on the immune response this vaccine is inducing and exactly how they believe it is inducing protection. I'd also be interested to know more about any animal testing they did, whether the vaccine was more or less effective in a non-human primate model (if those tests were done).
As an aside, I think the article is being misleading by focusing on the 16,000 number (total study participants) so much near the beginning and leaving the exploration of the numbers until the latter half. The important numbers are that 74 people (out of ~8200) in the placebo group got HIV and 51 people (out of ~8200) in the vaccine group got HIV. So, vaccine or no, only 125 people in the study actually contracted HIV at all. Now, subtract 51 from 74 to get 23 (difference in HIV infections between the two groups), divide 23 by 74 to get ~31% more patients in the placebo group that contracted HIV. The entire study pool may be ~16400, but the ~16275 participants who didn't get infected with HIV are completely irrelevant to the conclusions.
They describe it a little bit in the article (near the end, along with all of the actual important information), but the study cohort consists of a group of people who are likely to have a high risk of exposure to HIV. I can't speak to this study but, in other vaccine trials, commercial sex workers are a very common group to draw from, given their increased potential for exposure. The study then splits the overall group into two subgroups: One subgroup gets whatever the vaccine is, the other subgroup gets placebo (usually saline) injections that follow the same schedule as the actual vaccine. Both subgroups receive free condoms and educational materials. Researchers then compare the number of people in the vaccine subgroup that contract HIV to the number of people in the placebo subgroup that contract HIV. If the number of HIV infections in the placebo subgroup is greater than in the vaccine subgroup, researchers can conclude that the vaccine may be effective at reducing HIV infection. Usually in studies like this, IIRC, any participants who do become infected with HIV during the course of the study are also provided with appropriate treatment and medical care.
Obviously, this method isn't perfect, since there are a lot of variables that can't be controlled for and a lot of things that can't ethically be done with humans.
I'd imagine lots of test tube stuff before any human tests.
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