Houston doctors say they may have found a way to destroy HIV

Discussion in 'General Discussion' started by Dark_Convoy, Aug 2, 2008.

  1. Dark_Convoy

    Dark_Convoy Old Bastard Veteran

    Joined:
    Jul 1, 2002
    Posts:
    17,201
    Trophy Points:
    271
    Likes:
    +0
  2. Tekkaman Blade

    Tekkaman Blade Professor of Animation

    Joined:
    Jul 2, 2002
    Posts:
    21,945
    News Credits:
    13
    Trophy Points:
    337
    Location:
    Georgia
    Likes:
    +155
    Yes you inject yourself with 20,000 dollars.
     
  3. rattrap007

    rattrap007 Insert witty comment here TFW2005 Supporter

    Joined:
    Aug 18, 2002
    Posts:
    14,878
    News Credits:
    6
    Trophy Points:
    297
    Likes:
    +36
    "Are you sure?"
    "I'm not just sure. I'm HIV Positive it will work.."
     
  4. Lord Megatron

    Lord Megatron FFFF

    Joined:
    Sep 28, 2005
    Posts:
    1,640
    Trophy Points:
    161
    Likes:
    +0
    Awesome.
     
  5. Boardwise

    Boardwise is scary - Sig Killer - M Super Mod

    Joined:
    Dec 14, 2002
    Posts:
    24,333
    News Credits:
    6
    Trophy Points:
    311
    Likes:
    +6
    Ebay:
    Wow, this is good news.
     
  6. Chaos Muffin

    Chaos Muffin Misadventure Veteran

    Joined:
    Mar 26, 2004
    Posts:
    28,751
    Trophy Points:
    322
    Likes:
    +4
    Finally getting somewhere.

    If only they had ways to destroy all the cancer. That stuff takes too many of us out
     
  7. knook

    knook Let the Virus Consume You

    Joined:
    May 13, 2006
    Posts:
    3,579
    News Credits:
    13
    Trophy Points:
    201
    Likes:
    +13
    Ebay:
    That's known as a Christmas cracker joke
     
  8. Greyryder

    Greyryder Kitbashed

    Joined:
    May 9, 2004
    Posts:
    4,585
    Trophy Points:
    186
    Likes:
    +0
    Turns out that it doesn't really work against HIV, but it will kill vampires.
     
  9. Scantron

    Scantron Well-Known Member

    Joined:
    Oct 3, 2004
    Posts:
    8,249
    News Credits:
    3
    Trophy Points:
    211
    Likes:
    +3
    I realize that's an article written for lay-people, but there's really not a lot of information there about the specifics of how this works, such as exactly what protein in HIV is being targetted (looks like envelope, from the animation). Thankfully, the video is a little more instructive...although I still had to look up a couple of papers. Couple comments:

    - HIV doesn't just infect, replicate, kill the host cell and repeat the process. It can remain latent and non-replicating in some long-lived host cells (such as macrophage) for a long time and potentially reactivate later. The treatment described in this report will only deal with virus particles that are circulating in the blood, which might allow it to be a good preventative vaccine. For already infected patients, however, a few treatments might clear out the plasma viremia, but latent HIV could reactivate later, start replicating and cause viremia again later. Would chronic patients need repeated transfusions of these abzymes throughout their lives to suppress the virus?
    - Antibodies, which these abzymes are a variant of, can't normally penetrate some sites where HIV replicates, such as the brain. How is this treatment going to deal with that?
    - Not a specific critique of this treatment, but a cautionary note about getting hopes up (source)...
    ...like the treatment discussed in the opening article, the Merck vaccine looked great in the lab and it looked great in animal models. But that doesn't always translate out to success in human trials.
     
  10. Rodentus prime

    Rodentus prime Well-Known Member

    Joined:
    Jul 17, 2006
    Posts:
    5,416
    News Credits:
    6
    Trophy Points:
    282
    Location:
    Hants, UK
    Likes:
    +287
    It doesn't sound like it offers much more than current drug combinations which can also cut HIV in the blood down to undetectable levels but can't clear out the latent pockets of the virus hiding (eg in the brain).

    The main benefit would be if the virus can't become resistant to it as it can with drugs.
     
  11. Bryan

    Bryan ΜΟΛΩΝ ΛΑΒΕ

    Joined:
    Sep 8, 2005
    Posts:
    9,020
    Trophy Points:
    211
    Likes:
    +0
    We'll see.

    Not holding my breath right now, but here's hoping. If nothing else, figuring out something that doesn't work is still progress of a sort.
     
  12. theLostSeeker

    theLostSeeker Well-Known Member

    Joined:
    Jan 26, 2006
    Posts:
    1,994
    Trophy Points:
    161
    Likes:
    +0
    :lol 
    Cartman rules!
     

Share This Page